Department of Chemistry and Biochemistry

http://www.umsl.edu/chemistry/

Faculty

Gordon K. Anderson, Professor*, Chairperson
Ph.D., University of Glasgow
Lawrence Barton, Professor*
Ph.D., University of Liverpool
James S. Chickos, Professor*
Ph.D., Cornell University
Joyce Y. Corey, Professor*
Ph.D., University of Wisconsin
Wesley R. Harris, Professor*
Ph.D., Texas A. and M. University
David W. Larsen, Professor Emeritus*
Ph.D., Northwestern University
Robert W. Murray, Curators' Professor Emeritus*
Ph.D., Yale University
James J. O’Brien, Professor*
Ph.D., Australian National University
Christopher D. Spilling, Professor*
Ph.D., The University of Technology, Loughborough
Valerian T. D'Souza, Associate Professor*
Ph.D., University of Detroit
Cynthia M. Dupureur*, Associate Professor, Ph.D., Ohio State University
David L. Garin, Associate Professor Emeritus*
Ph.D., Iowa State University
Harold H. Harris, Associate Professor*
Ph.D., Michigan State University
Jane A. Miller, Associate Professor Emerita*
Ph.D., Tulane University
Keith J. Stine, Associate Professor*
Ph.D., Massachusetts Institute of Technology
Rudolph E. K. Winter, Associate Professor Emeritus*;
Ph.D., The Johns Hopkins University
Zhi Xu, Associate Professor*
Ph.D., University of Pittsburgh
F. Christopher Pigge, Associate Professor*,
Director of Graduate Studies
Ph.D., University of North Carolina
Alexei V. Demchenko, Assistant Professor*,
Ph.D., Zelinsky Institute for Organic Chemistry, Moscow
Joseph D. Dence, Adjunct Associate Professor
Ph.D. California Institute of Technology
Anthony Mannino, Adjunct Associate Professor
 Ph.D., Ohio State University 
Robert G. Orth, Adjunct Associate Professor
Ph.D., Case Western Reserve University
Nigam P. Rath, Research Associate Professor
Ph.D., Oklahoma State University
Janet B.  Wilking, Research Associate Professor*
Ph.D. Washington University
John Gutweiler, Lecturer
Ph.D., Saint Louis University
Technical Staff
Kenneth Owens, Glassblower
Joseph Kramer, Spectrometrist
Gordon Kerschmann, Electronics Technician
Donna Kramer, Coordinator, Laboratory Operations
Frank L. May, Research Investigator
Norman Windsor, Senior Electronics Technician

*members of Graduate Faculty

General Information

Degrees and Areas of Concentration
The Department of Chemistry and Biochemistry offers courses leading to the following baccalaureate degrees: B.A. in Chemistry

B.A. in Chemistry with a Biochemistry Certificate
B.S. in Chemistry, with a Chemistry or Biochemistry Option
B.S. in Education with an emphasis in Chemistry (in cooperation with the College of Education)
B.A. in Chemistry with teacher certification.

The department is accredited by the American Chemical Society. Students completing the B.S. degree (chemistry or biochemistry option) are certified to the American Chemical Society.  The B.S. degree is the professional degree in chemistry, and students who earn the B.S. degree are well prepared for a career in the chemical industry or for graduate work in chemistry.  The department provides opportunities for undergraduates to become involved in ongoing research projects and to participate in departmental teaching activities.

The department also offers graduate work leading to the M.S. or Ph.D. degree in chemistry with most graduate courses being scheduled in the evening.  A student may earn a M.S. degree with or without a thesis. The non-thesis option provides a convenient way for students who are employed full-time to earn an advanced degree.  Research leading to a M.S. thesis or Ph.D. dissertation may be conducted in one of four emphasis areas, namely, inorganic chemistry, organic chemistry, physical chemistry, or biochemistry.  The nature of the graduate program allows each student to receive individualized attention from his/her research mentor, and to develop hands-on experience with major instrumentation in the department.

Fellowships and Scholarships
The following scholarships, fellowships and awards are available to chemistry majors:

William and Erma Cooke Chemistry Scholarships are given annually to outstanding full-time chemistry majors who are at least sophomores and have financial need.

The Lawrence Barton Scholarship is given annually to a chemistry major who is enrolled in at least 9 credit hours per semester. Preference is given to juniors and to first generation college students, and to students who demonstrate financial need.

The Barbara Willis Brown Scholarship for Women in Chemistry is given to a female student over the age of 24, who is a chemistry major and has completed at least 60 credit hours. The student is expected to work with a faculty member on an undergraduate research project.

The Eric G. Brunngraber Memorial Scholarship is given to a chemistry major based on GPA, statement of research interests, and performance in completed course work.

Aid to Education Scholarships are given to junior or senior chemistry majors annually. The awardees are selected by the faculty on the basis of merit.

The M. Thomas Jones Fellowship is given each semester to the graduate student who is deemed by his/her peers to have presented the best research seminar.

The Graduate Research Accomplishment Prize is given annually.  The recipient is chosen based on his/her publications, presentations at professional meetings, and seminars given at UMSL.

Alumni Graduate Research Fellowships are available for summer study for selected chemistry graduate students.

Several undergraduate awards are given each year to outstanding students. The Chemical Rubber Company Introductory  Chemistry Award is given to the outstanding student in introductory chemistry, the American Chemical Society Division of Analytical Chemistry Award is given to the outstanding student in analytical chemistry, the American Chemical Society-St. Louis Section, Outstanding Junior Chemistry Major Award is given to the outstanding junior chemistry major, and the outstanding senior receives the Alan F. Berndt Outstanding Senior Award and the American Institute of Chemists Award.

Departmental Honors The Department of Chemistry and Biochemistry will award departmental honors to those B.A. and B.S. degree candidates in chemistry with an overall grade point average of 3.2. They must also successfully complete Chemistry 3905(290), Chemical Research, and must present an acceptable thesis.

Career Outlook
The St. Louis metropolitan area has long been a major center for industrial chemistry, and in the past decade it has become a focus for the establishment of life sciences research and development.  A bachelor’s degree in chemistry provides a student with the professional training needed to play a part in this ever-changing industry.

A major in chemistry provides excellent preprofessional training in the health sciences, and a double major in chemistry and biology is often chosen by premedical and predental students and those interested in graduate work in biochemistry and biology.  A minor in chemistry provides the minimum qualification and training for a position as a laboratory technician in industry, hospital laboratories, etc.

A Master’s degree in chemistry is often required for further advancement in the chemical industry, whereas a doctoral degree opens the door to many opportunities, including careers in the academic world, industrial research and development, and in government laboratories.

Undergraduate Studies

General Education Requirements
Students must satisfy the university and college general education requirements. Courses in chemistry may be used to meet the university's science and mathematics area requirement. The college's foreign language requirement fulfills the departmental requirements for B.A. candidates. It is recommended that candidates for the B.S. degree fulfill the language requirement in German or French, but any language, which meets the college requirement for the B.A. degree, is acceptable. Chemistry majors normally include Language 2101(101) in their foreign language sequence.

Satisfactory/Unsatisfactory Restrictions Chemistry majors may not take required chemistry, mathematics, or physics courses on a satisfactory/unsatisfactory basis, nor may B.S. degree candidates take the 2 elective hours in chemistry on this option.

Degree Requirements

Bachelor of Arts in Chemistry
This degree is intended primarily for preprofessional students in health science and related areas, as well as prelaw students interested in patent law. Candidates must complete the following chemistry courses:

1111(11), Introductory Chemistry I
1121(12), Introductory Chemistry II
2223(122), Quantitative Analysis
2412(241), Basic Inorganic Chemistry
2612(261), Organic Chemistry I
2622(262), Organic Chemistry II
2633(263), Organic Chemistry Laboratory
3022(202), Introduction to Chemical Literature
3312(231), Physical Chemistry I
3322(232), Physical Chemistry II
3333(233), Physical Chemistry Laboratory
4897(289), Seminar (1 credit)

In addition, candidates must complete one laboratory course chosen from Chemistry  3643(364), 4233(323), 4343(234), 4433(343), or 4733(373).

No more than 45 hours in chemistry may be applied toward the degree. Each chemistry major must present a seminar and pass a comprehensive examination during the senior year. The Department of Chemistry and Biochemistry may require students to pass a tracking test in order to enroll in the next level course, provided this or an equivalent test is administered to all students seeking to enroll in that course.

Bachelor of Arts in Chemistry with a Biochemistry Certificate
The university offers a certificate program for science majors who are interested in careers in biochemistry. This is an interdisciplinary program that involves additional courses in biochemistry and biology. In addition to the usual requirements for the B.A. degree in chemistry, the student must take the following courses: 

Chemistry
4712(371), Biochemistry
4722(372), Advanced Biochemistry
4733(373), Biochemistry Laboratory
4764(376), Interdisciplinary Topics in Biochemistry or
4772(377), Physical Biochemistry

Biology
1811(11), Introductory Biology I
2012(224), Genetics
3622(232), Cell Structure and Function
4602(326), Molecular Biology or
4614(327), Biotechnology Laboratory I

Students may obtain a minor in biology by adding Biology 1821(12) to the curriculum described above. The Biology department also offers a certificate in biochemistry.

Bachelor of Science in Chemistry.
This is the first professional degree in chemistry. It may be taken as a terminal degree by students intending to become professional chemists or for preparation for graduate work in chemistry or biochemistry. Students may choose to specialize in chemistry or biochemistry.

Chemistry Option
Candidates must complete the requirements for the B.A. degree in chemistry. In addition, the following chemistry courses are required:

3643(364), Advanced Organic Chemistry Laboratory
4212(321), Instrumental Analysis
4233(323), Laboratory in Instrumental Analysis
4343(234), Physical Chemistry Laboratory II
4412(341), Inorganic Chemistry I
4433(343), Inorganic Chemistry Laboratory
4712(371), Biochemistry

Students must also take two elective hours of advanced work in chemistry at the 3000 level or above. Students are encouraged to take Chem3905(290), Chemical Research, to fulfill the advanced elective requirement.

Biochemistry Option

Candidates must complete the requirements for the B. A. degree in chemistry. In addition, the following chemistry and biology courses are required:

Chemistry
4212(321), Instrumental Analysis
4233(323), Laboratory in Instrumental Analysis
4412(341), Inorganic Chemistry I
4712(371), Biochemistry
4722(372), Advanced Biochemistry
4733(373), Biochemistry Laboratory
4764(376), Interdisciplinary Topics in Biochemistry, or
4772(377), Physical Biochemistry or
3 credits of Chemistry 3905(290): Chemical Research, or 3 credits of Biology 4905(390): Research.

Biology
1811(11), Introductory Biology
2012(224), Genetics or
3622(232), Cell Structure and Function

If either research option is chosen, the project must be in biochemistry and must include a written final report submitted to the Department of Chemistry and Biochemistry.

Fifty-one hours of chemistry courses may be applied toward the degree. Each candidate must present a seminar and pass a comprehensive examination during the senior year.

Related Area Requirements

Bachelor of Arts and Bachelor of Science in Chemistry
Candidates for both degrees must also complete:

Math 1800(80), Analytic Geometry and Calculus I
Math 1900(175), Analytic Geometry and Calculus II
Math 2000(180), Analytic Geometry and Calculus III
Physics 1011(111), Physics: Mechanics and Heat
Physics 1012(112), Physics: Electricity, Magnetism, and Optics

B.S. degree in Secondary Education with an Emphasis in Chemistry
All candidates must enroll in a program that includes Levels I, II, and III course work in the College of Education. In addition, students must complete the following Science Core Courses and those listed under Chemistry Endorsement:

Science Core Courses:
Philosophy 3380(280), Philosophy of Science
Biology 1811(11), Introductory Biology I
Biology 1821(12), Introductory Biology II
Chemistry 1111(11), Introductory Chemistry I
Chemistry 1121(12), Introductory Chemistry II
Geology 1001(1), General Geology
Atmospheric Science 1001(001), Elementary Meteorology
Biology 1202(120), Environmental Biology, or another environmental science
Physics 1011(111), Physics: Mechanics and Heat
Physics 1012(112), Physics: Electricity, Magnetism, and Optics

Chemistry Endorsement
Chemistry 2223(122), Quantitative Analysis
Chemistry 2612(261), Organic Chemistry I
Chemistry 2622(262), Organic Chemistry II
Chemistry 2633(263), Organic Chemistry Laboratory
Chemistry 3312(231), Physical Chemistry I
Chemistry 4712(371), Biochemistry
Chemistry 4802(280) or Education 3240(240), Methods of Teaching Science in Secondary Schools
Chemistry 4837(283), Teaching Intern Seminar

Bachelor of Arts in Chemistry with Teacher Certification Students must complete the B.A. in chemistry requirements, as well as the requirements for teacher certification. (See the College of Education section of this Bulletin.)

Minor in Chemistry
Requirements for the Minor
Students may earn a minor in chemistry by completing the following program. The following five courses are required:

Chemistry
 1111(11), Introductory Chemistry I
 1121(12), Introductory Chemistry II
2223(122), Quantitative Analysis
2612(261), Organic Chemistry I
2633(263), Organic Chemistry Laboratory

One course from the following list must be completed:

Chemistry
2412(241), Basic Inorganic Chemistry
2622(262), Organic Chemistry II
3312(231), Physical Chemistry I
4712(371), Biochemistry same as Biology 4712(371)

Courses, which are prerequisites to subsequent courses in the minor, may not be taken on a satisfactory/ unsatisfactory basis. A GPA of at least 2.0 is required for the courses presented for the minor. At least three courses toward the minor must be completed at UM-St. Louis.

Graduate Studies

Admission Requirements
Individuals with at least the equivalent of the B.A. degree in chemistry may be admitted to the Graduate School as candidates for the M.S. degree or as precandidates for the Ph.D. degree in chemistry. A student in the M.S. program  may request to transfer to the Ph.D. program by petition to the department.

The department admissions committee considers applicants' grade point averages and normally requires above-average performance in all areas of chemistry as well as physics and mathematics, or other evidence of high aptitude for graduate work in chemistry. Applicants' GRE scores, letters of recommendation, and academic programs are also considered. In some cases the committee may require successful completion of undergraduate course work as a condition of enrollment as a regular student.

Students with bachelor's degrees in fields other than chemistry may be admitted to pursue graduate studies in chemistry, but they must make up background deficiencies, usually by taking undergraduate course work.

Financial Support
Teaching assistantships are available to qualified applicants. Research assistantships and fellowships are available for advanced students. For further information, contact the Graduate Studies Committee, Department of Chemistry and Biochemistry.

Preliminary Advisement
Students who have been admitted for graduate work in chemistry will be contacted by the Director of Graduate Studies in order to develop a tentative plan of study which takes into consideration the student's background and

interests. Entering students are required to demonstrate proficiency at the undergraduate level in four areas of chemistry (organic, inorganic, physical, and analytical).

Proficiency may be demonstrated in one of the following ways:

  • Outstanding performance in recent undergraduate course work.
  • Satisfactory performance in standardized placement examinations. These examinations are given twice a year, approximately one week before the beginning of the fall and winter semesters.
  • Successful completion of assigned course work.

The ultimate choice of whether students may enroll in the M.S. or Ph.D. degree programs resides with the chemistry faculty.

Distribution Requirement Students must take chemistry courses for graduate credit at the 4000(300) or 5000(400) level, including at least one in three of the four areas of chemistry: organic, inorganic, physical, and biochemistry.  Inorganic Chemistry I Chem 4412(341) may not be used to satisfy this distribution requirement.

Master's Degree Requirements

Master of Science in Chemistry Candidates for the M.S. degree in chemistry must demonstrate proficiency in organic, inorganic, physical, and analytical chemistry within two years of initial enrollment.

A minimum of 30 hours is required, normally including 3 hours in Chem 6897(489) Chemistry Colloquium. No more than 3 hours in Chem 6897(489) may be applied toward the required minimum of 30 credit hours.

Master of Science in Chemistry with Thesis
Students selecting this option must be enrolled full-time for at least two consecutive semesters. During this time, students are expected to enroll in Chem 6905(490), Graduate Research in Chemistry, and conduct their thesis research.  A maximum of 12 hours of Chemistry 6905(490) may be applied toward the required 30 hours. At least 9 hours must be at the 5000(400) level, excluding Chemistry 6905(490). A maximum of 9 hours in 3000(200) level or above courses outside the department may be accepted if students receive prior approval of their advisers and the Director of Graduate Studies.  Students are expected to follow all other general requirements of the Graduate School regarding master’s degree and thesis requirements.

Master of Science without Thesis
Unlike the thesis option, students need not be enrolled full-time. Of the required 30 hours, 15 credits must be at the 5000(400) level. A maximum of 6 credits of Chemistry 6905(490), Graduate Research in Chemistry, may be included in place of 4000(300) level courses. A maximum of 12 hours taken in 3000(200) level or above courses outside the department may be accepted with prior approval of the Director of Graduate Studies.

Doctoral Degree Requirements
Incoming doctoral students must demonstrate proficiency in organic, inorganic, physical, and analytical chemistry within one year of initial enrollment.  A minimum of 60 hours is required, including research hours.

Cumulative Examinations
In addition to the Ph.D. requirements set forth by the Graduate School, students seeking the Ph.D. in chemistry must take a series of cumulative examinations given eight times a year. Students must pass at least two examinations per year and a total of eight examinations by the end of their third year in the Ph.D. program. At least six of these examinations should be in the student's specialization area. The examinations are usually given the second Saturday of each month, September through April. The mechanism for designing and deciding on passing and failing grades for each examination resides with faculty members in each specialization area.

Seminar Requirement
Students must present a seminar in their third year and during each subsequent year. The third year seminar may be the defense of the doctoral dissertation proposal. One of the seminars is for the purpose of describing dissertation research. Students must enroll in Chemistry 6897(489), Chemistry Colloquium, each semester they are in residence.

Advancement to Candidacy
In addition to general Graduate School requirements for advancement to candidacy, students must complete the following:

1) 21 hours of nondissertation work. This may not include:
Chem 4212(321), Instrumental Analysis
Chem 4233(323), Laboratory in Instrumental Analysis
Chem 4412(341), Inorganic Chemistry I
Chem 4433(343), Inorganic Chemistry Laboratory
Chem 6196(419), Advanced Reading in Chemistry
Chem 6487(448), Inorganic Problem Seminar
Chem 6687(468), Organic Problem Seminar
Chem 6787(478), Biochemistry Problem Seminar
Chem 6812(481), Introduction to Graduate Study in Chemistry
Chem 6822(482), Introduction to Graduate Research in   Chemistry
Chem 6897(489), Chemistry Colloquium

but should include at least one in three of the four areas of chemistry: organic, inorganic, physical, and biochemistry. Courses in areas other than chemistry may be included with prior departmental approval.

2) Pass eight cumulative examinations.

3) Present at least one seminar to the department on the dissertation research.

4) Participate in the undergraduate academic program as a teaching assistant for at least one semester.

5) Be in good standing.

Dissertation
Four copies of the dissertation must be submitted upon completion of the graduate research problem.

Probation and Dismissal
Students are dismissed from the program if they fail to pass the required number of cumulative examinations before the end of each year as precandidates for the Ph.D. or otherwise fail to meet the standards set forth by the Graduate School.


Course Descriptions

Prerequisites may be waived by consent of the department or instructor. Some courses as indicated in the course description may be taken concurrently with the listed offering. Consult your adviser for further information.

Students who have earned 24 or more semester hours of credit at any accredited post-secondary institutions(s) before the start of the fall 2002 semester must meet the general education requirements stipulated in the UM-St Louis 2001-2002 Bulletin.  The following courses fulfill the Natural Sciences and Mathematics breadth of study requirements as described in that Bulletin:

1011(10), 1082(1), 1091(9), 1111(11), 1121(12), 1134(13), 2223(122), 2412(241), 2612(261), 2622(262), 2633(263), 3022(202), 3312(231), 3322(232), 3333(233), 3643(364),  3814(381), 3905(290), 4212(321), 4233(323), 4343(234), 4412(341), 4433(343), 4652(365), 4712(371), 4722(372), 4733(373), 4764(376), 4772(377), 4897(289),

1011(10) Chemistry in the Environment and Everyday Living (3)  [MI, MS]
This course examines the role of chemistry in everyday life and in the environment, and is intended for students not pursuing scientific or engineering majors. Chemical principles are introduced to the extent necessary for understanding of issues, but this course does not provide the basis for further technical courses. Two hours of lecture per week; on alternate weeks, one hour of discussion or two hours of laboratory.

1052(5) Chemistry for the Health Professions (4) [MI, MS]
An introduction to general, nuclear, structural organic, organic reactions and biochemistry. This course is designed primarily for students in nursing and related health professions, and should not be taken by students majoring in the physical or biological sciences. Chemistry majors may include neither Chemistry 1052(5) nor1062 (6) in the 120 hours required for graduation. Four hours of lecture per week.

1062(6) Organic and Biochemistry for the Health Professions (2) [MI, MS]
Prerequisites: any college chemistry course. An introduction to organic reactions and biochemistry. Chemistry 1062(6) is offered during the second half of the semester. Four hours of lecture per week.

1082(1) General Chemistry I (3) [MI, MS]
Prerequisite: Satisfactory score on math placement test. A broad introductory survey of chemical principles. Chem 1 1082(001-plus Chem 1091(9) are equivalent to Chem 1111(11). This alternative may be attractive to students who are not mathematically prepared for Chem 1111(11). Chemistry majors may not include both Chem 1082(1) and 1111(11) in the 120 hours required for graduation. Three hours of lecture per week.

1091(9) General Chemistry II (3) [MI,  MS]
Prerequisites: Chem 1082(1) (or equivalent or consent of instructor) and Mathematics 1030(30) and 1035(35) (may be taken concurrently). Additional work on the topics of Chem 1082(1), with emphasis on quantitative material. Introduction to the chemical laboratory. Chem 1082(1) plus Chem 1091(9) is equivalent to Chem 1111(11) for science majors. Chemistry majors who receive credit for Chem 1082(1) and Chem 1091(9) may not also include Chem 1011(10) or Chem 1111(11) in the 120 hours required for graduation. No student may take both Chem 3 and Chem 9(1091) for credit. Two hours of lecture per week, three and one-half hours of lab or one hour of discussion on alternate weeks.

1111(11) Introductory Chemistry I (5) [MS]
Prerequisites: Mathematics through college algebra and trigonometry may be taken concurrently. Presents an introduction to the fundamental laws and theories of chemistry. Laboratory experiments are designed to demonstrate some aspects of qualitative and quantitative analysis and to develop skills in laboratory procedures. Chemistry majors may not include both Chem 1082(1) and 1111(11), nor both Chem 1011(10) and 1111(11) in the 120 hours required for graduation. Three hours of lecture and one hour of discussion per week; one hour of laboratory-lecture and three hours of laboratory per week.

1121(12) Introductory Chemistry II (5) [MI, MS]
Prerequisite: Chem 1111(11) or advanced placement. Lecture and laboratory are a continuation of Chem 1111(11). Three hours of lecture and one hour of discussion per week; one hour laboratory-lecture and three hours of laboratory weekly.

1134(13) Special Topics in Introductory Chemistry (1-5)
Prerequisite: Consent of instructor. A lecture or laboratory course to assist transfer students in meeting the requirements of Chem 1111(11) and 1121(12).

2223(122) Quantitative Analysis (3)  [C, MI, MS]
Prerequisite: Chem 1121(12). Principles and practice of elementary quantitative chemistry. The lecture treats descriptive statistics with emphasis on small samples; various types of competing equilibria pertaining to acid-base, complexometric and potentiometric titrations; and an introduction to spectrophotometric processes. The laboratory provides exercises in titrimetric, gravimetric, and spectrophotometric techniques. Both portions of the course deal with the analytical chemistry of environmentally-significant problems. Two hours of lecture and four and one-half hours of laboratory weekly.

2412(241) Basic Inorganic Chemistry (2) [MI, MS]
Prerequisites: Chem 1121(12). Review of principles of atomic structure, covalent and ionic bonding. Properties of the elements and synthesis, reactions and bonding aspects of important compounds of main group and transition metal elements.

2612(261) Organic Chemistry I (3) [MS]
Prerequisite: Chem 1121(12). An introduction to the structure, properties, synthesis, and reactions of aliphatic and aromatic carbon compounds. Three hours of lecture per week.

2622(262) Organic Chemistry II (3) [MI, MS]
Prerequisite: Chem 2612(261). A systematic study of organic reactions and their mechanisms; organic synthetic methods. Three hours of lecture per week.

2633(263) Organic Chemistry Laboratory (2) [C, MS]
Prerequisite: Chem 2612(261) or consent of instructor. An introduction to laboratory techniques and procedures of synthetic organic chemistry including analysis of organic compounds. One hour of lecture and four and one-half hours of laboratory per week.

3022(202) Introduction to Chemical Literature (1)
Prerequisite: Chem 2622(262) may be taken concurrently and Chem 2412(241). The course will familiarize the student with the literature of chemistry and its use. One hour of lecture per week.

3312(231) Physical Chemistry I (3)
Prerequisites: Chem 2223(122) and Physics 1011(111). Math 2000(180) may be taken concurrently. Principles of physical chemistry including thermodynamics, theory of gases, phase equilibria, kinetics, crystal structure, spectroscopy, and quantum mechanics. Three hours of lecture per week.

3322(232) Physical Chemistry II (3)
Prerequisite: Chem 3312(231). Continuation of Chem 3312(23). Three hours of lecture per week.

3333(233) Physical Chemistry Laboratory I (2)
Prerequisite: Chem 3312(231) may be taken concurrently. Experiments designed to illustrate principles introduced in Chem 3312(231). One hour of lecture and four and one-half hours of laboratory per week.

3643(364) Advanced Organic Chemistry Laboratory (2)
Prerequisites: Chem 2223(122), Chem 2622(262), Chem 2633(263). Chem 3022(262) may be taken concurrently. Identification of organic compounds by classical and spectroscopic methods; advanced techniques in synthesis and separation of organic compounds. One hour of lecture and four and one-half hours laboratory per week. Not for graduate credit.

3814(381) Special Topics (1-10)
Prerequisite: Consent of instructor. A reading and seminar course in selected advanced topics.

3905(290)  Chemical Research (1-10)
Prerequisite: Consent of instructor. Independent laboratory and library study, in conjunction with faculty member, of fundamental problems in chemistry. A written report describing the research is required.

4212(321) Instrumental Analysis (2)
Prerequisite: Chem 3322(232). Principles and applications of modern methods of instrumental analysis for analytical chemistry measurements. Topics will be selected from the areas of electrochemistry, absorption and emission spectroscopy, chromatography, mass spectrometry, surface analysis, and nuclear magnetic resonance. Two hours of lecture per week.

4233(323) Laboratory in Instrumental Analysis (2)
Prerequisites; Chem 4212(321) and 3333(233). Experiments designed to illustrate the principles and practices of instrumental analysis, involving the use of modern instrumentation in analytical chemistry applications. One hour of discussion and four and one-half hours of laboratory per week.

4343(234) Physical Chemistry Laboratory II (2)
Prerequisites: Chem 3322(232) may be taken concurrently and 3333(233). Experiments designed to illustrate principles introduced in Chem 2322(232). One hour of lecture and four and one-half hours of laboratory per week. Not for graduate credit.

4412(341) Inorganic Chemistry I (3)
Prerequisites: Chem 3322(232) may be taken concurrently, 2412(241) and 2622(262). An introduction to the chemistry of the elements, including atomic and molecular structure, acids and bases, the chemistry of the solid state, and main group and transition metal chemistry. Three hours of lecture per week.

4433(343) Inorganic Chemistry Laboratory (2)
Prerequisites: Chem 3333(233), 4412(341) and 3643(364) 3643(364) may be taken concurrently. The more sophisticated techniques of physical and analytical chemistry will be used to study inorganic compounds and their reactions. One hour of lecture and four and one-half hours of laboratory per week.  Not for graduate credit.

4652(365) Spectroscopic Identification of Organic Compounds (3)
Prerequisite: Chem 3643(364). An applied approach to the use of spectroscopic techniques in organic chemistry. Topics to include integrated applications of infrared and Raman spectroscopy, nuclear magnetic resonance 13C and 1H, cw and pulsed and mass spectroscopy for the purpose of elucidating the structure of organic compounds. Three hours of lecture per week.

4712(371) Biochemistry (3)
Same as Biology 4712(371) Prerequisite: Chem 2612(261) and either Biology 1811(11) or Chem 2622(262). The chemistry and function of cell constituents, and the interaction and conversions of intracellular substances. Three hours of lecture per week. Students may not receive credit for both Biology 4712(371) and Chemistry 4712(371). Biology 4712(371) may not be used to fulfill the 3000 or 4000 (300)) level lecture course requirement for the B.S. in Biology.

4722(372) Advanced Biochemistry (3)
Prerequisite: Chem 4712(371). Selected advanced topics in the chemistry of life processes. Three hours of lecture per week.

4733(373) Biochemistry Laboratory (2)
Prerequisite: Chem 4712(371) may be taken concurrently. Laboratory study of biochemical processes in cellular and subcellular systems with emphasis on the isolation and purification of proteins (enzymes) and the characterization of catalytic properties. One hour of lecture and three and one-half hours of laboratory per week.

4764(376) Interdisciplinary Topics in Biochemistry (3)
Prerequisites: Chem 4712(371); Chem 4722(372) strongly recommended. Includes advanced studies of enzyme mechanisms, the role of metal ions in enzymatic and non-enzymatic processes, and the application of computational chemistry to biological systems. Three hours of lecture per week.

4772(377) Physical Biochemistry (3)
Prerequisite: Chem 3312(231) or Chem/Bio 4712(371). Designed to acquaint students with concepts and methods in biophysical chemistry. Topics that will be discussed include protein and DNA structures, forces involved in protein folding and conformational stability, protein-DNA interactions, methods for characterization and separation of macromolecules, electron transfer, and biological spectroscopy. Three hours of lecture per week.

4802(280) Curriculum and Methods of Teaching Physical Sciences (3)
Prerequisites: Tch Ed 3310(310) and a near major in the subject matter. A study of the scope and sequence of the physical science courses in the school curriculum, with emphasis on the selection and organization of materials and methods of instruction and evaluation. Attention is also directed toward learning the techniques and research tools of the scholar in the field of science. To be taken prior to student teaching. This course must be completed in residence.

4837(283) Chemistry / Physics Teaching Intern Seminar (1)
Same as Physics 4833(283). Prerequisite: Chem 4802(280) or Physics 4800(280). A seminar to accompany student teaching covering integration of physical science curricula and methods into the classroom setting. To be taken concurrently with Secondary Student Teaching, Sec Ed 3290(290). One-hour discussion per week.

4897(289) Seminar (1)
Prerequisites: Chem 3022(202) and senior standing. Presentation of papers by students, faculty, and invited speakers. Chemistry majors must enroll during the semester in which they intend to graduate. Completion of a comprehensive examination is a course requirement. One hour of lecture and one hour of discussion per week.

5142(414) Molecular Spectroscopy (3)
Prerequisite: Chem 3322(232). A broad treatment of the interaction of electromagnetic radiation with matter, emphasizing the unity of such interactions. Interpretation of molecular rotational, vibrational and electronic spectra in terms of geometric structure and dynamics. Description and interpretation of physical techniques used to obtain molecular spectra. Three hours of lecture per week.  

5162(416) Chemical Applications of Group Theory (3)
Prerequisite: Chem 3322(232). A brief introduction to the fundamental relationships of group theory and molecular symmetry. Application of group theory to molecular orbital theory, molecular vibrations, and molecular spectra. Three hours of lecture per week.

5302(430) Advanced Physical Chemistry (3)
Prerequisite: Chem 3322(232). Covers advanced topics in physical chemistry. May include but is not limited to properties of solids and liquids, gas/solid and solid/liquid interfacial chemistry, optical and electron spectroscopy, and chemical dynamics. Three hours of lecture per week.

5322(432) Application of Thermodynamics and Reaction Kinetics in Chemistry (3)
Prerequisite: Chem 3322(232). Review of equilibrium thermodynamics. Focus is on statistical thermodynamics and reaction kinetics with an emphasis on solution phase chemistry. Three hours of lecture per week.

5394(439) Special Topics in Physical Chemistry (1-3)
Prerequisite: Consent of instructor. Selected topics in physical chemistry. May be taken more than once for credit.

5412(441) Typical Element Chemistry (3)
Prerequisite: Chem 4412(341) or an equivalent course. Chemistry of the main group elements and their compounds including such topics as electron deficient compounds, acids, bases and nonaqueous solvents, catenation and inorganic polymers, the solid state, organotypical element chemistry and energetics. Three hours of lecture per week.

5432(443) Spectroscopic Methods in Inorganic Chemistry (3)
Prerequisites: Chem 4412(341) or an equivalent course. Study of modern spectroscopic characterization methods of particular importance to inorganic systems, with emphasis on such techniques as multinuclear NMR spectroscopy, UV/visible and EPR spectroscopy, IR/Raman spectroscopy, and Mossbauer spectroscopy. Application of such methods to questions of structure, bonding and reactivity. Three hours of lecture per week

5442 (422) Coordination Chemistry (3)
Prerequisite: Chem 4412(341) or an equivalent course. Chemistry of the coordination compounds of the transition metals including such topics as kinetics and mechanisms of reaction, stereochemistry, ligand field theory, stability and electronic spectra. Three hours of lecture per week.

5452(435) Quantum Mechanical Foundations of Spectroscopy (3)
Prerequisites: Chem 3322(232). A review of relevant principles and techniques of quantum mechanics. Focus is on the use of quantum theory and molecular symmetry (group theory) to understanding the structure and interpreting the spectra of atoms and molecules. Three hours of lecture per week.

.5452(445) Organometallic Chemistry of the Main Group Elements (3)
Prerequisites: Chem 4412(341) or an equivalent course. A systematic study of main group element compounds containing carbon-metal or carbon-metalloid bonds. Emphasis will be on preparative methods, structures and reactions of various classes of compounds. Three hours of lecture per week.

5462(446) Organometallic Chemistry of the Transition Elements (3)
Prerequisites: Chem 4412(341) or an equivalent course. A study of the transition metal compounds containing metal-carbon bonds and related metal-element bonds, including their synthesis, structure and bonding, and reactions. Applications in organic synthesis and catalysis will also be presented. Three hours of lecture per week.

5494(449) Special Topics in Inorganic Chemistry (1-3)
Prerequisite: Consent of instructor. Selected topics in inorganic chemistry. May be taken more than once for credit.

5602(460) Advanced Organic Chemistry I - Physical Organic (3)
Prerequisites: Chem 2622(262) and 3322(232) Mechanism and theory of organic chemistry. Topics to include kinetics, transition state theory, reaction intermediates, and stereochemical analysis. Three hours of lecture per week.

5612(461) Advanced Organic Chemistry II - Reactions and Synthesis (3)
Prerequisite: Chem 2622(262). Examination of a variety of organic transformations typically utilized in organic synthesis. Topics will include carbon-carbon bond formation, pericyclic reactions, oxidation, reduction, and functional group interconversions. Mechanism and stereochemistry will be emphasized. Three hours of lecture per week

5694(469) Special Topics in Organic Chemistry (3)
Prerequisite: Consent of instructor. Advanced topics of special current interest. May be taken more than once for credit. Topics that may be offered include: methods of organic synthesis, organometallics in organic synthesis, topics in bioorganic chemistry, organic thermochemistry, natural products chemistry, stereochemistry, photochemistry, heterocyclic chemistry, medicinal chemistry.

5794(479) Special Topics in Biochemistry (1-3)
Prerequisite: Consent of instructor. Selected topics in biochemistry. May be taken more than once for credit.

6196(419) Advanced Reading in Chemistry (1)
Prerequisite: Admission to the Ph.D. degree program. Reading and examinations in the subdisciplines of chemistry. Enrollment must begin after completion of any course deficiencies.

6487(448) Problem Seminar in Inorganic Chemistry (1)
Prerequisite: Consent of the inorganic chemistry staff. Problems from the current literature, presentations, and discussions by faculty, students and visiting scientists. Ph.D. students may take more than once for credit. Up to three credits may be applied to the M.S. degree program.

6687(468)  Problem Seminar in Organic Chemistry (1)
Prerequisite: Consent of the organic chemistry staff. Problems from the current literature, presentations, and discussions by faculty, students, and visiting scientists.  Ph.D. students may take more than once for credit. Up to three credits may be applied to the M.S. degree program

6787(478) Problem Seminar in Biochemistry (1)
Prerequisites: Consent of the biochemistry staff. Problems from the current literature, presentations and discussions by faculty, students and visiting scientists. Ph.D. students may take more than once for credit. Up to three credits may be applied to the M.S. degree program.

 6812(481) Introduction to Graduate Study in Chemistry (1)
Prerequisite: Consent of Graduate Adviser. Topics to be covered include: techniques of teaching of Chemistry in colleges and universities, methods of instruction and evaluation; and responsibilities of the Graduate Teaching Assistant in laboratory instruction; safety in the undergraduate laboratory, safety practices, emergency procedures; selection of research project and thesis adviser.

6822(482) Introduction to Graduate Research in Chemistry (1)
Prerequisites: Consent of Graduate Adviser. Topics include: safety in the research laboratory, safety practices, emergency procedures, hazardous materials, waste disposal, radiation safety; research ethics; chemistry information retrieval, computer assisted information retrieval, types of databases, searching bibliographic data bases.

6897(489) Chemistry Colloquium (1)
Presentation of papers by students, faculty, and invited speakers. One hour per week.

6905(490) Graduate Research in Chemistry (1-10)